United States securities and exchange commission logo November 29, 2022 Steven Feng Chief Financial Officer NIO Inc. Building 20, 56 Antuo Road Jiading District, Shanghai 201804 People s Republic of China Re: NIO Inc. Form 20-F for the period ended December 31, 2021 File No. 1-38638 Dear Steven Feng: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Manufacturing